An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein ...
Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...
Then Deliberately Hands It Over to Humans Subway Customer Stunned After Noticing Both ‘Recycling’ and ‘Trash’ Slots End Up in ...
CagA disrupts bacterial biofilms. It also prevents Aβ and α-synuclein from forming fibrils. Scientists will test CagA in AD and PD mouse models to assess its therapeutic potential. Scientists estimate ...
Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...
Hello and thanks for sharing this massive work. I want to try your AI driven simulation to analyse the stability of a monomer protein. My starting point is a structure predicted by e.g. ESMfold, ...
Immunogenicity refers to a biopharmaceutical’s ability to generate an immune response upon administration. It is a major concern in biologics development because it can cause adverse events in ...
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In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.
# Replace $MULTICOM4_INSTALL_DIR with your MULTICOM4 installation directory bash $MULTICOM4_INSTALL_DIR/tools/alphafold-v2.3.2/scripts/download_all_data.sh <YOUR ...