Something is off with 49ers receiver Brandon Aiyuk this year. He says it's because defenses are playing him differently. Some ...

The Patriots are taking their shot at the reigning NFC champions today. Here’s everything you need to know before Pats-49ers.

Aiyuk had two receptions on five targets for 48 yards in Sunday's 30-13 win over the Patriots. Aiyuk's early slog through the fantasy schedule continued for a fourth week despite the 49ers picking up ...

The San Francisco 49ers are back to .500, but there is still plenty of criticism directed at star wide receiver Brandon Aiyuk ...

For a few precious seconds, the mystique returned to Levi’s Stadium. As Fred Warner raced 45 yards down the right sideline with an interception early in Sunday’s second quarter, leaping over the pylon ...

San Francisco 49ers WR Brandon Aiyuk dove for the catch from QB Brock Purdy against the New England Patriots in Week 4.

The NFL fined the Los Angeles Rams $100,000 after two players, including an inactive player, shoved 49ers receiver Brandon ...

New England Patriots safety Jabrill Peppers makes a leaping interception in coverage against San Francisco 49ers wide ...

The Los Angeles Rams have been hit with a significant fine over a sideline incident that occurred at the end of their win ...

San Francisco 49ers wide receiver Brandon Aiyuk scoops up a tough catch from quarterback Brock Purdy against the New England Patriots.

San Francisco 49ers DL Nick Bosa took down New England Patriots quarterback during the team's Week 4 matchup. San Francisco ...

San Francisco 49ers quarterback Brock Purdy finds wide receiver Brandon Aiyuk for a 38-yard gain against the New England Patriots. Watch the best catches from Houston Texans wide receiver Nico Collins ...