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  1. Apolipoprotein E - Wikipedia

    Apolipoprotein E (Apo-E) is a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in Alzheimer's disease and cardiovascular diseases. [5] . It is encoded in …

  2. What is APOE, how is it related to Alzheimer's disease, and ...

    Apolipoprotein E, or APOE, is a gene that comes in several forms, or alleles: APOE2, APOE3, and APOE4. Everyone carries 2 copies of this gene, one from each of their biological parents. …

  3. Multifaceted roles of APOE in Alzheimer disease - PMC

    For the past three decades, apolipoprotein E (APOE) has been known as the single greatest genetic modulator of sporadic Alzheimer disease (AD) risk, influencing both the average age …

  4. APOE gene: A major driver in Alzheimer's disease

    6 days ago · Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers.

  5. The proportion of Alzheimer’s disease attributable to ...

    6 days ago · Variation in the APOE gene strongly affects Alzheimer’s disease (AD) risk. However, the proportion of AD burden attributable to this variation requires clarification, which would …

  6. APOE4 and APOE3 gene variants linked to at least 7 in 10 ...

    6 days ago · A new study into the APOE gene suggests two variants may influence Alzheimer's and dementia risk more than previously thought.

  7. Alzheimer's Risk May Be Driven by a Single Gene - Medpage Today

    5 days ago · Most Alzheimer's disease and nearly half of all dementia was associated with variations in the APOE gene, a study of 470,000 older adults suggested. In all-cause …