Jun 21, 2019 · Hall CN, Reynell C, Gesslein B, Hamilton NB, Mishra A, Sutherland BA, O'Farrell FM, Buchan AM, Lauritzen M, Attwell D. Capillary pericytes regulate cerebral blood flow in …

May 23, 2017 · Takahisa Kanekiyo Mayo Clinic Posted: 19 May 2017 News: Finally, a Dye to Visualize Pericyte Function Dr. Grutzendler’s group found that Nissl dye NeuroTrace 500/525 …

Feb 10, 2018 · Loss of pericytes, delicate cells that surround the smallest blood vessels in the brain, may contribute to white-matter disease, a breakdown of the myelinated neurons in the …

Jun 22, 2023 · The thalamus (yellow), entorhinal cortex (green), and hippocampus (cyan) contain fewer endothelial cells and pericytes and more fibroblasts and ependymal cells than other …

Nov 3, 2017 · This popular mouse model overexpresses human APP with two mutations linked to familial Alzheimer's disease (the Swedish and Indiana mutations). Transgene expression is …

Aug 19, 2020 · Bridging pericytes are described in the recent preprint by Hartmann et al., who reported that ablation of bridging pericytes dilate both the proximal and distal capillaries, which …

This database is a repository of variants in genes implicated in Alzheimer’s disease (AD). Currently, it includes the three genes associated with autosomal-dominant AD (APP, PSEN1, …

Jan 5, 2026 · The study focuses primarily on endothelial cell-autonomous effects, even though FOXF2 is also enriched in pericytes, where SVD risk genes frequently converge. Whether …

Jun 29, 2020 · The Tsai lab examined vascular amyloid deposition with a three-dimensional model of the blood-brain barrier using endothelial cells, mural cells (pericytes and vascular …

May 2, 2014 · Pericyte proliferation, migration, and recruitment to the vascular wall is regulated by the growth factor PDGFβ, and therefore, genetic disruption of the PDGFβ receptor gene …